CAS No: 69-65-8
Molecular Formula: C₆H₁₄O₆
Molecular Weight: 182.17 g/mol
Synonyms: Mannite, D-Mannitol, Osmitrol, Manna sugar, Mannit.
Appearance: White crystalline powder or granule.
Purity: ≥ 99.0% (HPLC).
Mannitol is a hexanol with a sweet taste. Because of the absorption of heat during the dissolution, it has a comfortable feeling to the mouth, so it is widely used in the manufacture of chewable tablets such as antialcoholic medicine and mouth cooling agent. Mannitol granules are used as excipients for direct compression in tablets and Mannitol can be used as base materials for nitroglycerin tablets.
Our D-Mannitol Powder is a white crystalline, odorless, and sweet-tasting polyol (sugar alcohol) widely used in pharmaceutical, food, and industrial applications. It is known for its excellent stability, low hygroscopicity, and cooling effect.
We are a professional manufacturer and global supplier of high-purity mannitol powder (Mannitol Pulver), offering both pharmaceutical grade and food grade types. With years of experience in sugar alcohol production, we provide reliable bulk supply, full certification (COA, SDS, GMP, ISO), and customized packaging to meet your specific application needs. Contact us.
| Mannitol Standard | ||||
| ITEM | CP2015 | BP2018 | EP9.2 | USP41 |
| Appearance | white crystals or crystalline power,odorless | |||
| Solubility | Freely soluble in water,very slightly soluble in ethanol | |||
| Identification:Melting point | 166~170℃ | 165~170℃ | 165~170℃ | |
| Specific optical rotation | +137°~+145° | +23°~+25° | +23°~+25° | |
| Identification:FeCl3 | Positive | —— | —— | |
| Identification:Infrared absorption spectrophotometry | Conformity | |||
| Identification:TLC | —— | Conformity | Conformity | |
| Acidity | Conformity | —— | —— | |
| Appearance of solution | Clear and colourless | |||
| Related substance | ≤2.0% | Conformity | Conformity | |
| Reducing sugars | ≥12.8ml | ≤0.1% | ≤0.1% | |
| Chloride | ≤0.003% | —— | ||
| Sulphate | ≤0.01% | —— | ||
| Oxalate | ≤0.02% | —— | ||
| Loss on drying | ≤0.5% | ≤0.5% | ≤0.5% | |
| Residue on lgnition | ≤0.1% | —— | ||
| Heavy metals | ≤10ppm | —— | —— | |
| Arsenic | ≤2ppm | —— | —— | |
| Conductivity | —— | ≤20us/cm | ≤20us/cm | |
| Nickel | —— | ≤1ppm | ＜1ug/g | |
| Assay | 98.0~102.0% | 97.0~102.0% | 97.0~102.0% | |
| Bacterial endotoxins | —— | ＜2.5cuf/g | ＜2.5cuf/g | |
| The total viable aerobic count | —— | ≤100us/cm | ≤100us/cm | |
| Molds and yeasts | —— | ≤100us/cm | ≤100us/cm | |
| Escherichia coli | —— | Negative/g | Negative/g | |
| Salmonella | —— | Negative/10g | Negative/10g | |
Mannitol is widely used as a low-calorie sweetener and sugar substitute in sugar-free candies, chocolate coatings, chewing gums, baked goods, and diabetic-friendly foods.
It also serves as an anti-caking agent and moisture control ingredient, improving product texture and stability during storage.
Mannitol powder(Pulver) is used as raw materials for large volume parenterals, to produce Mannitol Injection, which has the efficacy of reducing intracranial pressure, intraocular pressure and diuresis.
As filler and excipient, Mannitol is used in tablets for Anticancer medicine, Antibacterial medicine, Antihistamines medicine, Vitamins, Antialcoholic medicine, Refreshing agent.
As cerebral vasodilator, Mannitol is for the treatment of cerebral vascular infarction.
As diuretics, Mannitol is a mild laxative, it has special effects on oliguria and renal function deline caused by edema and burns.
Chemical synthesis intermediates
Analytical reagents
Microbiological media preparation
Surface coating and anti-caking applications in industrial processes
Mannitol is one of the main products of Shijazhuang Huaxu Pharmaceutical CO., LTD. with good price and quality, factory direct sales. Our company is a professional supplier and from China manufacturer, with various products on sale and Cheap. Our mannitol powder production follows strict GMP and ISO 9001 quality management standards.
Direct factory supply – competitive price & stable supply chain
Food grade & pharmaceutical grade options available
Full documentation: COA, SDS, MSDS, Halal, Kosher, ISO, GMP
Custom particle size and packaging service
Fast global shipping: EXW / FOB / CIF / DDP terms available
Low MOQ & sample support
Technical guidance and formulation assistance
We provide free or paid samples (100–500 g) for quality evaluation and formulation testing. Please provide your target purity, particle size, and grade when requesting a quote.
Q1: What is the difference between food grade and pharmaceutical grade mannitol?
Pharmaceutical grade mannitol meets stricter purity and microbiological limits according to pharmacopeial standards (USP, EP). Food grade is intended for general food processing and sugar replacement applications.
Q2: Is mannitol suitable for diabetic products?
Yes. Mannitol has a low glycemic index and does not raise blood glucose levels significantly, making it suitable for diabetic and keto-friendly food products.
Q3: Can I request a customized particle size or packaging type?
Yes. We offer custom milling, sieving, and repackaging services. Please specify your requirements when requesting a quote.
