Shijiazhuang Huaxu Pharmaceutical Co.,Ltd
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Where can Sorbitol be used
Sorbitol, alias sorbitol. It is white hygroscopic powder or crystalline powder, flakes or granules, odorless. According to different crystallization conditions, the melting point changes in the range of 88~102℃, and the relative density is about 1.49. It is easily soluble in water (1g is dissolved in about 0.45mL of water), and slightly soluble in ethanol and acetic acid.
It has a cool sweetness, the sweetness is about half of that of sucrose, and the calorific value is close to that of sucrose. In the food industry, it is mostly Sorbitol liquid with a content of 69~71%. Sorbitol liquid is a clear and colorless syrupy liquid with sweet taste, neutral to litmus, miscible with water, glycerin and propylene glycol. Can be used as nutritive sweetener, humectant, chelating agent and stabilizer.
Sorbitol can be used as a pharmaceutical excipient. It can be compatible with a variety of adjuvants and is widely used in solid dispersing agents, fillers, wetting agents, diluents, plasticizers for capsules, sweeteners, and ointment substrates. . The following will take you to understand the effects of Sorbitol in four kinds of pharmaceutical excipients:
Both Sorbitol and Mannitol are hypertonic dehydrating diuretics with the effect of dilating extracellular fluid solvents. The Chinese Pharmacopoeia stipulates that clinical mannitol infusion is a 20% supersaturated solution. Mannitol infusion is easy to crystallize and separate below 20°C, while the room temperature in most parts of my country is lower than 20°C in winter. It needs to be preheated to dissolve before medication, which not only causes difficulties in clinical medication, especially emergency medication, but also easily leads to suspicion of patients. cause conflicts between doctors and patients.